Actively Recruiting

Phase 3
Age: 21Years - 60Years
All Genders
NCT06979141

Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia

Led by Al-Azhar University · Updated on 2025-06-11

300

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.

CONDITIONS

Official Title

Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia

Who Can Participate

Age: 21Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 21-60 years
  • Both genders
  • Body mass index < 30 kg/m2
  • American Society of Anesthesiology (ASA) physical status I-II
  • Mallampati score class I or II
  • Patients undergoing surgery under general anesthesia
Not Eligible

You will not qualify if you...

  • Known allergy to study drugs
  • History of psychiatric illness
  • Patients with major organ diseases
  • Pre-existing neurological deficits
  • Body mass index > 30 kg/m2
  • Active airway infection or history of tracheal and laryngeal surgery
  • Lower esophageal sphincter incompetence and reflux
  • Increased intracranial and intraocular pressure
  • Use of cough-inducing medications
  • Pregnant and lactating women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Medicine, Al-Azhar university Assiut, Egypt.

Asyut, Egypt, 2091110

Actively Recruiting

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Research Team

M

Medhat H Allam, lecturer.MD

CONTACT

O

Osama H Ahmed, Professor.MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia | DecenTrialz