Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07556133

Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

Led by Saint-Joseph University · Updated on 2026-04-29

1000

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this prospective, randomized, single-blinded is to learn if there is an ideal sedation protocol in cataract surgery in adults. The main questions it aims to answer are: * Does the combination of Dexmedetomidine and Propofol affect significantly Ramsay sedation scale, compared to Dexmedetomidine and compared to Propofol? * How does each sedation protocol affect hemodynamics? (Heart rate and blood pressure) * Are respiratory events more common in a certain group? * Is the surgeon's satisfaction similar among groups? * Are adverse effects (bradycardia, hypotension, nausea) more common in a certain group? Researchers will compare 3 sedation protocols : Dexmedetomidine versus Propofol versus the combination of these 2 drugs and to see if one protocol is overall superior to the others. Fentanyl will also be used in all 3 sedation protocols. Participants will : * Receive one of these three protocols * Be operated for one or both eyes * Monitored during the whole surgery and in the recovery room * Be evaluated by the Ramsay sedation scale by a trained Anesthesiologist or CRNA during surgery and in the recovery room Surgeons will be asked about how much they were satisfied.

CONDITIONS

Official Title

Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults undergoing cataract surgery
Not Eligible

You will not qualify if you...

  • Severe hepatic insufficiency
  • Third degree AV block
  • Patient refusal

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
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3
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Trial Site Locations

Total: 1 location

1

Hotel-Dieu de France

Beirut, Lebanon

Actively Recruiting

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Research Team

R

Rhea Nacouzi, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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