Actively Recruiting

Phase 4
Age: 20Years - 65Years
All Genders
Healthy Volunteers
NCT06636578

Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block

Led by Fayoum University · Updated on 2024-10-15

90

Participants Needed

2

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In 2012 Blanco et al. \[1\] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries. PECS block includes PECS I and PECS II (modified PECS I) interfascial blocks. Since that time, PECS block has been used successfully with good results for a wide variety of surgeries on the chest wall such as radical mastectomies, breast-conserving surgeries, breast implant placement, automated implantable cardioverter-defibrillator (AICD)/pacemaker placement, intercostal drainage tube placement, and rib fractures. In this study, the investigators hypothesized that adding dexmedetomidine as an adjuvant to ropivacaine can result in the prolongation of the duration of anesthesia with improvement of the quality of postoperative analgesia of bilateral PECS block for patients undergoing cardiac surgery via midline sternotomy compared with using only plain ropivacaine.

CONDITIONS

Official Title

Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block

Who Can Participate

Age: 20Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 20 to 65 years
  • Ejection fraction greater than 35%
  • Elective isolated coronary artery bypass grafting (CABG) or valve surgery
Not Eligible

You will not qualify if you...

  • Poor left ventricular function requiring intra-aortic balloon pump support
  • Recent myocardial infarction within the last seven days
  • Combined heart or vascular procedures along with CABG
  • Emergency surgery or redo cases
  • Liver or kidney failure with creatinine levels above 1.5
  • Hemodynamic instability
  • Infection at the site of nerve block
  • Allergy to local anesthetics
  • Psychiatric illness
  • Prolonged postoperative ventilatory support

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Fayoum University Hospital

Al Fayyum, Egypt, 63511

Completed

2

Mohamed Hamed

Al Fayyum, Egypt, 63511

Actively Recruiting

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Research Team

M

mina fam, M.D

CONTACT

M

Mostafa Elhamamsy, M.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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