Comparing Dexmedetomidine and Dexamethasone with Bupivacaine for Nerve Block During Thyroid Surgery

What this Trial Is About

This research aims to compare the safety and effectiveness of two drugs, dexmedetomidine and dexamethasone, as additions to bupivacaine for pain control in patients undergoing total thyroidectomy. The study focuses on patients who experience pain after thyroid surgery, which can delay hospital discharge and impact both patients and healthcare providers. It is a phase four, randomized, double-blind clinical trial involving 60 patients. Participants are divided into two groups one group receives a bilateral intermediate cervical plexus block with bupivacaine plus dexmedetomidine, and the other group receives bupivacaine plus dexamethasone. The nerve block is guided by ultrasound to provide pain relief during and after surgery. Both treatments are administered under general anesthesia. Throughout the study, researchers will measure pain levels using the Numeric Pain Rating Scale 24 hours after surgery, tracking median, range, mean, and standard deviation scores. They will also monitor drug-related side effects during this same period. The study is designed to evaluate pain relief effectiveness and safety of these adjuvants to improve recovery after thyroidectomy. Participation spans the surgery and immediate postoperative period with monitoring focused on the first 24 hours after operation.

Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block