Actively Recruiting
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block
Led by Damanhour Teaching Hospital · Updated on 2026-01-12
60
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Many thyroidectomy patients suffer from postoperative pain that could delay early hospital discharge and place a significant burden on both the patient and the healthcare team. Bilateral intermediate cervical plexus block (ICPB) provides good analgesia for neck surgery, including thyroidectomy. However, the duration of a single-shot nerve block is usually short. Therefore, adjuvants are used in peripheral nerve blocks. Objectives: To compare the safety and efficacy of dexmedetomidine versus dexamethasone as adjuvants to bupivacaine in ultrasound-guided intermediate cervical plexus block in patients undergoing total thyroidectomy under general anesthesia. Patients and Methods: This is a randomized, double-blind, phase four, prospective clinical trial; carried out on 60 patients, who were candidates for total thyroidectomy under general anesthesia at our hospital. Patients were randomly allocated into two equal groups; group A, received bilateral ICPB with isobaric bupivacaine plus dexmedetomidine, and group B, received bilateral ICPB with isobaric bupivacaine plus dexamethasone.
CONDITIONS
Official Title
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block
Who Can Participate
Eligibility Criteria
You may qualify if you...
- American Society of Anesthesiologists (ASA) physical status 64 II
- Age from 21 to 60 years
- Body Mass Index (BMI) 64 35 kg/m2
You will not qualify if you...
- ASA physical status > II
- Age < 21 years or > 50 years
- Body Mass Index (BMI) > 35 kg/m2
- Bronchial asthma
- Chronic obstructive pulmonary disease
- Restrictive lung diseases
- Sick sinus syndrome
- Sinus bradycardia
- Hypertension
- Chronic hypotension
- Ischemic heart disease
- Coagulopathies
- Hepatic insufficiency
- Renal insufficiency
- Diabetes mellitus
- Peripheral neuropathy
- Thyroid malignancy
- Hyperthyroidism
- Substernal goiter
- Patients on beta-blockers
- Patients using pacemakers
- Alcohol or drug abuse
- Allergy to the study drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Damanhour Teaching Hospital
Damanhūr, El-Beheira, Egypt
Actively Recruiting
Research Team
A
Ahmed M Shaat, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here