Actively Recruiting
Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries
Led by Sohag University · Updated on 2025-05-20
84
Participants Needed
1
Research Sites
44 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to compare the efficacy, safety and overall effectiveness of dexmedetomidine and dexmedtomidine and ketamine (ketodex) in achieving controlled hypotension during Ear and nose surgeries. \- Assessment the analgesic and sedative role of both drugs.
CONDITIONS
Official Title
Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 60 years scheduled for elective ear and nose surgeries requiring controlled hypotensive anesthesia
- American Society of Anesthesiologists (ASA) physical status I or II
- Undergoing specific ear and nose surgeries where controlled hypotensive anesthesia is indicated
- Stable cardiovascular health without uncontrolled hypertension, hypotension, or ischemic heart diseases
You will not qualify if you...
- Severe cardiovascular diseases such as congestive heart failure, uncontrolled hypertension, arrhythmias, or ischemic heart diseases
- Any cardiac patients
- Significant respiratory conditions like chronic obstructive pulmonary disease or severe asthma
- Known allergies to dexmedetomidine, ketamine, or study drug components
- Pregnant or breastfeeding women
- Use of chronic medications affecting blood pressure or interacting with study drugs (e.g., beta-blockers, MAO inhibitors)
- Chronic liver or kidney diseases
- Severe psychiatric or neurological disorders affecting consent or study outcomes
- History of substance abuse, especially sedatives or opioids
- Coagulation disorders or use of anticoagulant therapy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Faculty of medicine
Sohag, Egypt
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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