Actively Recruiting

Phase Not Applicable
Age: 18Years - 95Years
All Genders
NCT02994160

DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)

Led by University of Texas Southwestern Medical Center · Updated on 2026-03-05

25

Participants Needed

1

Research Sites

665 weeks

Total Duration

On this page

Sponsors

U

University of Texas Southwestern Medical Center

Lead Sponsor

D

Defense Advanced Research Projects Agency

Collaborating Sponsor

AI-Summary

What this Trial Is About

Our goal is to temporarily implant the following groups for 540 +/- 30 days: 1. Forearm FAST electrodes 1. Five human partial hand amputees (amputated at the level of the hand) with 2 FAST electrodes in the ulnar nerve and 2-5 FAST electrodes in the median nerve. 2. Five human hand and forearm amputees (amputated at the level of the forearm) with 2 FAST electrodes in the ulnar nerve and 2-5 FAST electrodes in the median nerve . 2. Arm FAST electrodes 1. Five human partial hand amputees (amputated at the level of the hand) with 2 FAST electrodes in the ulnar nerve and 2-5 FAST electrodes in the median nerve. 2. Five human hand and forearm amputees (amputated at the level of the forearm) with 2 FAST electrodes in the ulnar nerve and 2-5 FAST electrodes in the median nerve. 3. Five human hand, forearm and arm amputees (amputated at the level of the arm) with 2 FAST electrodes in the ulnar nerve and 2-5 FAST electrodes in the median nerve.

CONDITIONS

Official Title

DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)

Who Can Participate

Age: 18Years - 95Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female, age 18 and older, of any race or ethnicity
  • Able and willing to sign Consent
  • Able and willing to participate in all study activities including implantation, testing and explantation of the study device
  • Able to communicate effectively in English without an interpreter
  • Overall and phantom pain are well-controlled and not incapacitating
Not Eligible

You will not qualify if you...

  • Nerve or muscle dysfunction/injury above the amputation stump level as shown by MR neurogram and EMG/NCS studies
  • Unsuitable bony anatomy of the amputation stump based on radiographs
  • History of cardiac arrhythmia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UT Southwestern Medical Center

Dallas, Texas, United States, 75390

Actively Recruiting

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Research Team

D

Debby Noble

CONTACT

J

Jennifer Barillas

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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