Actively Recruiting
Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis
Led by Satu Mare County Emergency Hospital · Updated on 2025-02-20
100
Participants Needed
1
Research Sites
174 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial aims to learn if a combination of Dextran 40 and Ringer's lactate solution can improve fluid resuscitation in mild and moderate acute pancreatitis (AP) and prevent complications. The main questions it aims to answer are: Does early fluid resuscitation with Dextran 40 plus Ringer's lactate improve patient outcomes compared to Ringer's alone? Does this treatment reduce inflammation, organ failure, and the need for intensive care unit (ICU) admission? Researchers will compare Dextran 40 plus Ringer's lactate to Ringer's alone to see if the combination therapy is more effective in reducing disease severity and complications. Participants will: Receive either Dextran 40 plus Ringer's lactate (1:3 ratio) or Ringer's lactate alone. Have blood tests every 24 hours to measure inflammation and organ function. Be monitored for changes in disease severity, need for ICU admission, and hospitalization duration. This study will help determine the best fluid resuscitation strategy for treating mild and moderate acute pancreatitis.
CONDITIONS
Official Title
Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older diagnosed with mild or moderate acute pancreatitis
- Must provide written informed consent for study participation
You will not qualify if you...
- Patients who decline to provide informed consent
- Patients who are non-compliant with treatment and follow-up visits
- Pregnant individuals
- Patients requiring treatments that are not allowed in this study
- Patients who develop conditions preventing use of the study medication
- Patients with severe adverse reactions requiring stopping treatment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Spitalul Judetean de Urgenta Satu Mare
Satu Mare, Satu Mare County, Romania, 440067
Actively Recruiting
Research Team
C
Costea Cristian PHD STUDENT, MEDICNE
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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