Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05278494

Dextromethorphan for Treatment of Postoperative Pain

Led by Nathanael Heckmann · Updated on 2026-03-27

160

Participants Needed

1

Research Sites

224 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan compared to Placebo for the Treatment of Postoperative Pain

CONDITIONS

Official Title

Dextromethorphan for Treatment of Postoperative Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older planning to undergo total knee arthroplasty
  • American Society of Anesthesiologists (ASA) classes I to III
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) of 35 or higher
  • History of opioid abuse
  • History of severe vomiting after previous surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Keck School of Medicine of USC

Los Angeles, California, United States, 90033

Actively Recruiting

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Research Team

P

Pui Yan, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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