Actively Recruiting
Diabetes RElated to Acute Pancreatitis and Its Mechanisms
Led by Milton S. Hershey Medical Center · Updated on 2025-11-18
800
Participants Needed
13
Research Sites
419 weeks
Total Duration
On this page
Sponsors
M
Milton S. Hershey Medical Center
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overriding objective of DREAM is to conduct a prospective longitudinal (36 months) observational clinical study to investigate the incidence, etiology, and pathophysiology of diabetes mellitus (DM) following acute pancreatitis (AP).
CONDITIONS
Official Title
Diabetes RElated to Acute Pancreatitis and Its Mechanisms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of acute pancreatitis within 0 to 90 days before enrollment
- Ability to understand and participate in all study activities including informed consent, case report forms, telephone interviews, metabolic testing, and follow-ups
You will not qualify if you...
- Definite chronic pancreatitis diagnosed by CT, MRI, or MRCP showing pancreatic calcifications or ductal abnormalities
- Hospitalization for less than 48 hours due to post-ERCP acute pancreatitis
- Previous direct endoscopic or percutaneous necrosectomy or drainage of pancreatic necrosis before enrollment
- Presence of pancreatic tumors including ductal adenocarcinoma, neuroendocrine tumors, or metastasis
- Confirmed or suspected cystic tumor causing pancreatic duct dilation or acute pancreatitis
- Prior pancreatic surgeries such as distal pancreatectomy, pancreaticoduodenectomy, necrosectomy, or Frey procedure
- Use of disallowed medications within 30 days before enrollment as per study manual
- Severe systemic illnesses including past organ transplant, AIDS, recent cancer treatment (except skin cancer), severe kidney disease, cirrhosis, or other conditions with life expectancy under 12 months
- Known pregnancy at enrollment
- Incarceration
- Any condition that compromises participant safety or study integrity
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 13 locations
1
University of Southern California
Los Angeles, California, United States, 90033
Actively Recruiting
2
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
3
Stanford University
Stanford, California, United States, 94305
Actively Recruiting
4
University of Florida
Gainesville, Florida, United States, 32610-0214
Actively Recruiting
5
AdventHealth
Orlando, Florida, United States, 32804
Actively Recruiting
6
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
7
University of Illinois at Chicago
Chicago, Illinois, United States, 60612
Actively Recruiting
8
Indiana University
Indianapolis, Indiana, United States, 46202
Actively Recruiting
9
Johns Hopkins University
Baltimore, Maryland, United States, 21205
Actively Recruiting
10
University of Minnesota
Minneapolis, Minnesota, United States, 55454
Actively Recruiting
11
Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
12
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
13
Benaroya Research Institute
Seattle, Washington, United States, 98101
Actively Recruiting
Research Team
M
Melissa A Butt, DrPH
CONTACT
K
Kendall T Baab, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here