Actively Recruiting

Age: 18Years +
All Genders
NCT05765786

Diagnosing Variable Primary Aldosteronism.

Led by Queen Mary University of London · Updated on 2025-06-08

100

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to see if there is a cyclical or exaggerated diurnal variation in aldosterone production in people with Primary Aldosteronism.

CONDITIONS

Official Title

Diagnosing Variable Primary Aldosteronism.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • People with clinically suspected Primary Aldosteronism (PA) who have not met diagnostic criteria, based on low renin (renin activity <0.5 nmol/h/L or renin mass <5 ng/L), plasma sodium >140 mmol/L, or plasma potassium <4 mmol/L
  • Patients diagnosed with PA who had previous aldosterone samples less than 277 pmol/L, which usually would not qualify for confirmatory testing
  • Patients with aldosterone test results done at different times showing variable production
  • Willingness to consent and participate in the study
Not Eligible

You will not qualify if you...

  • Inability to stop beta-adrenoceptor antagonist therapy for 2 weeks
  • Patients receiving end-of-life treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Queen Mary University of London

London, United Kingdom

Actively Recruiting

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Research Team

Y

Yun Ni Lee

CONTACT

T

Tumi Kaminskas

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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