Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06128681

Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique

Led by Dan Liu · Updated on 2026-02-10

30

Participants Needed

1

Research Sites

265 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to learn whether patients undergoing mediastinal disease diagnosis and combined treatment with intrapacial ultrasound-guided mediastinal opening techniques have greater clinical benefit. The main questions it aims to answer are: * Whether the mediastinal ultrasound-guided mediastinal opening technique is more beneficial for the diagnosis of benign or malignant mediastinal diseases. * Does the mediastinal ultrasound-guided mediastinal opening technique benefit the patient by ablating mediastinal masses using freezing, laser, or other means. Mediastinal diseases were diagnosed by lymph node biopsy combined with NGS, ROSE and other techniques using transairway ultrasound-guided mediastinal opening technique. Ablation of mediastinal malignancies is performed using techniques such as freezing or laser. Transbronchial lung biopsy(TBLB) may also be performed when necessary. Researchers will compare the experimental group with mediastinal opening and the control group without mediastinal opening to see if Mediastinal open technique benefits patients.

CONDITIONS

Official Title

Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Radiographic abnormalities of mediastinum
  • Can tolerate general anesthesia
  • Can tolerate bronchoscopy and has the condition to have mediastinal biopsy and treatment
Not Eligible

You will not qualify if you...

  • Imaging or other tests can make a definitive diagnosis
  • Cannot tolerate general anesthesia or tracheoscopic surgery
  • Patients cannot sign informed consent forms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tianjin Medical University General Hospital

Tianjin, China, 300000

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique | DecenTrialz