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Age: 0 - 18Years
All Genders
ID03398629

Study of Diagnosis and Care for Intrauterine Growth Restriction and Congenital Anomalies Following Babies from Before Birth to 18 Years Old

Led by Guangzhou Women and Children's Medical Center · Updated on 2019-06-04

10000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to build a large platform combining clinical information and biological specimen banks for fetuses and infants diagnosed with intrauterine growth restriction IUGR or congenital anomalies. These conditions are significant causes of infant and childhood death, and this study seeks to understand their occurrence, progression, and relationship from before birth through early childhood. The goal is to provide a foundation for accurate diagnosis, precision treatment, and careful management of these conditions. Pregnant women and infants diagnosed with IUGR or various congenital anomalies including structural and chromosomal anomalies are enrolled. Routine obstetrical ultrasounds monitor fetal growth, and detailed maternal information, including dietary habits and exposures, is collected. After birth, infants receive appropriate treatments and regular physical and neurological examinations. Biological samples such as maternal blood, placenta, cord blood, infant blood, urine, stool, and tissues are collected and stored for research. Genetic testing is also conducted to explore disease causes and guide treatment. Participants undergo ongoing assessments including growth and development measurements, clinical outcome tracking, and evaluation of treatment effects on hospitalization and health. Data are collected via intelligent extraction platforms and analyzed using machine learning and statistical methods to improve prenatal diagnosis accuracy and identify prognostic markers. The study includes follow-ups up to several years to observe recovery and quality of life, supporting improved prevention and care strategies.

CONDITIONS

Brief Title

Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women with prenatal diagnosis of intrauterine growth restriction (IUGR)
  • Pregnant women or neonates/infants diagnosed with structural anomalies
  • Pregnant women or neonates/infants diagnosed with chromosomal anomalies
  • Participants must deliver at Guangzhou Women and Children's Medical Center
  • Neonates and infants up to 18 years old with the above diagnoses
Not Eligible

You will not qualify if you...

  • Pregnant women who do not agree to participate
  • Pregnant women delivering babies at hospitals other than Guangzhou Women and Children's Medical Center
  • Cases where prenatal suspected anomalies are not confirmed by postnatal diagnosis

Research Team

W

Wei Zhong, Master

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