Actively Recruiting

Age: 18Years - 69Years
All Genders
Healthy Volunteers
NCT06670261

Diagnosis of Respiratory Disorders by the Numerical Modeling.

Led by University Hospital, Bordeaux · Updated on 2025-04-24

300

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Bordeaux

Lead Sponsor

C

CREATIS Laboratory

Collaborating Sponsor

AI-Summary

What this Trial Is About

Chronic Nasal obstruction (CNO) is not currently measurable objectively because clinicians use validated declarative self-questionnaires whose results are linked to the level of understanding, the acute or chronic clinical situation, fatigue, psychological state and the desired gain. Using numerical simulations of the passage of air in the nasal cavities determining specific airflow parameters, the respiratory comfort of healthy subjects and the CNO of patients treated for this pathology could be explained.

CONDITIONS

Official Title

Diagnosis of Respiratory Disorders by the Numerical Modeling.

Who Can Participate

Age: 18Years - 69Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 69 years
  • Body mass index (BMI) less than 30 kg/m2
  • Caucasian ethnic origin or from the Mediterranean region
  • Asymptomatic with or without septal deviation and NOSE score 7 or less
  • Patients with chronic nasal obstruction from morphological causes needing surgery with NOSE score 9 or higher
  • Patients may have sleep apnea with Apnea-hypopnea index 20 or less and no other cause of apnea
Not Eligible

You will not qualify if you...

  • Acute or chronic rhinosinusitis with or without polyps (except controlled allergic rhinitis)
  • Vasculitis
  • Empty nasal cavity syndrome
  • Septal perforations
  • History of nasal plastic surgery, sinonasal endoscopic surgery, or head/neck cancer radiotherapy
  • Uncontrolled bronchopulmonary disease
  • Treatments affecting nasal vasomotor function

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Bordeaux

Bordeaux, France

Actively Recruiting

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Research Team

L

Ludovic De GABORY, Pr

CONTACT

E

Elodie BELMO

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Diagnosis of Respiratory Disorders by the Numerical Modeling. | DecenTrialz