Actively Recruiting

Age: 18Years +
All Genders
NCT05144152

Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA)

Led by Chinese University of Hong Kong · Updated on 2024-08-27

600

Participants Needed

1

Research Sites

182 weeks

Total Duration

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AI-Summary

What this Trial Is About

The investigators aim to evaluate the diagnostic accuracy of FIT and the novel panel of four bacterial gene markers collectively named as M3, to detect recurrent advanced adenomas in patients with history of colonic adenomas.

CONDITIONS

Official Title

Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Known colorectal adenomas during index colonoscopy
  • Available baseline M3 and FIT results before index colonoscopy
  • Aged 18 years or older
  • Written informed consent obtained
Not Eligible

You will not qualify if you...

  • Refusal or unfit to undergo surveillance colonoscopy
  • Incomplete colonoscopy, incomplete removal of colorectal adenomas, or inadequate bowel preparation (Boston Bowel Preparation Scale score 0 or 1 in any colonic segment) at index colonoscopy
  • Previous colonic resection
  • Personal history of colorectal cancer
  • Personal history of polyposis syndrome
  • Personal history of inflammatory bowel disease
  • Known pregnancy or lactation
  • Advanced comorbid conditions (American Society of Anesthesiologists grade 4 or above)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Prince of Wales Hospital

Shatin, New Territories, Hong Kong

Actively Recruiting

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Research Team

M

Min Dai

CONTACT

C

Connie Seto

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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