Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06420960

Diagnostic Cost-Effectiveness of Connected Watch ECG Compared to 48-Hour External Holter ECG for Symptomatic Palpitations Without Electrocardiographic Documentation

Led by L'hôpital Nord-Ouest - Villefranche Villefranche sur Saône · Updated on 2025-04-08

81

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the diagnostic effectiveness and cost efficiency of using connected watch ECG monitoring compared to the conventional 48-hour external Holter ECG for patients experiencing palpitations without documented electrocardiographic traces. Palpitations are a common reason for emergency consultations, but their transient and infrequent nature makes diagnosis challenging. This study aims to compare how well these two strategies identify the cause of arrhythmias six months after cardiological consultation. All participants will wear a standard 48-hour Holter ECG monitor and also receive a connected watch for a six-month period. They will be instructed to record ECG tracings with the connected watch only when experiencing symptoms. The Holter ECG records continuously for 48 hours, while the watch provides extended monitoring and allows up to three symptom-triggered ECG transmissions. Participants will be supported in using the watch and the associated Health Mate app and contacted two months into the study to assess understanding, compliance, and any adverse events. During the study, participants will complete event forms and transmit ECG recordings when symptomatic. Researchers will evaluate the rate at which the connected watch identifies arrhythmias compared to the Holter ECG, along with types of diagnoses and the time healthcare professionals spend per diagnosis. The primary outcome is measured at six months or when the watch is returned. The study includes follow-up calls and data collection on diagnosis rates and medical time to assess the cost-effectiveness of the connected watch strategy.

CONDITIONS

Brief Title

Diagnostic Efficacy of Connected WAtch ECG Versus External Holter ECG

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Any patient consulting primarily for palpitations without a previous arrhythmia diagnosis, or with different symptoms from a prior arrhythmia diagnosis
  • Palpitations requiring cardiological consultation or emergency hospital treatment
  • No suggestive diagnosis on intercritical 12-lead ECG (e.g., pre-excitation, high-grade atrioventricular block, atrial fibrillation with heart rate >110 bpm)
  • Non-contributory stress test if symptoms occur during exercise
  • Willing to wear the connected watch all the time except during charging
  • Owns a personal smartphone or tablet compatible with the Health Mate app and internet connection
  • Affiliated with a social security system
  • Provides dated and signed informed consent form
Not Eligible

You will not qualify if you...

  • Refusal to wear the connected watch
  • Refusal to use the study-provided watch due to personal connected watch use
  • Unable to use the connected watch (lack of understanding of its use)
  • No smartphone available
  • Wearer of implantable cardiac device (pacemaker or defibrillator)
  • Known and treated arrhythmia with identical symptoms
  • Heart disease requiring implantable device for prevention
  • Associated syncope
  • Obvious non-cardiac cause for symptoms
  • Pregnant or breastfeeding women
  • Unable to complete study follow-up due to geographical, linguistic, social, or psychological reasons
  • Participation in another interfering clinical study
  • Patient under guardianship or deprived of liberty

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 48 hours for Holter ECG; connected watch monitoring for 6 months

Participants receive a connected watch and a 48-hour Holter ECG monitor to record ECG data when symptoms occur. They are instructed on device use and supported in setting up the Health Mate application.

1 visit for device setup (in-person) and a follow-up phone call at 2 months

Long-term Monitoring

Duration - Up to 6 months

Participants wear the connected watch for up to 6 months to capture symptomatic ECG recordings and are monitored for diagnostic outcomes and device compliance.

Participants record ECGs during symptoms; follow-up phone call at 2 months

Trial Site Locations

Total: 1 location

1

Hopitaux Nord-Ouest Villefranche Sur Saone

Gleizé, France, 69400

Actively Recruiting

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Research Team

O

OLIVIER LE VAVASSEUR, MEDECINE

C

COLINE PERRIER, ARC

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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