Feasibility Study of 100 Hz Tetanic Stimulation Using Electromyography in Patients With Normal and Abnormal Nerve Function During Surgery

What this Trial Is About

Researchers are investigating the use of 100 Hz tetanic stimulation with an electromyography EMG device to study postoperative residual neuromuscular block in anaesthetized patients. The study aims to find out if fatigue develops with this stimulation in patients who have either normal or abnormal baseline electroneurographic ENG findings. This research also explores how chronic conditions affecting peripheral nerves, like polyneuropathy, may impact the tests usefulness. During the study, the ulnar nerve at the carpal tunnel is stimulated supramaximally, and the electric response of the abductor digiti minimi muscle is recorded using the Alpine Biomed ENG-EMG device with Keypoint software. Patients are grouped based on their initial ENG results into normal or abnormal ENG groups. Tetanic stimulation at frequencies of 60 and 100 Hz is applied for 5 seconds to assess responses. Participants undergo ENG testing after anesthesia induction, with monitoring lasting up to one hour during anesthesia. No further ENG measurements occur postoperatively. The study evaluates the 100 Hz tetanic fade response and the diagnostic feasibility of EMG in assessing the neuromuscular safety margin. Participants arms are positioned and prepared for electrode placement following standard procedures.

Diagnostic Feasibility of 100 Hz Tetanic Stimulation