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Evaluating Mitral Annulus Velocity Changes by Tissue Doppler to Detect Fluid Response During Initial Shock Treatment in Emergency Patients
Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2025-12-04
187
Participants Needed
1
Research Sites
20 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the use of mitral annulus velocity variation E measured by tissue Doppler ultrasound as a diagnostic tool to evaluate fluid responsiveness in patients admitted to the emergency department with shock. Shock is characterized by low blood pressure requiring vascular filling, and assessing how patients respond to fluid filling is a critical challenge in emergency medicine. This observational study aims to determine if changes in E before and after fluid filling can accurately identify patients who benefit from such treatment. During the study, patients with shock and mean arterial pressure below 65 mmHg who require vascular filling will undergo three cardiac ultrasounds. The first ultrasound occurs at the start of a 500 mL fluid infusion, the second immediately after the infusion ends, and the third 20 minutes later. These ultrasounds are part of standard care and are used to monitor heart function and fluid response. The study focuses on measuring the change in E velocity around the time of fluid administration. Participants will be monitored through these ultrasound assessments during their initial management in the emergency department. The main outcomes measured are the variation in E velocity and fluid filling responsiveness at the time of inclusion. Additional monitoring includes a later E measurement. The study seeks to improve diagnostic methods for fluid responsiveness in emergency care, with participation lasting during the initial emergency treatment period.
CONDITIONS
Brief Title
Diagnostic Performance of the Mitral Annulus Velocity Variation Measured by Tissue Doppler to Evaluate the Fluid Responsiveness During the Initial Management of Shock in Patients Admitted to the Emergency Department
Research Team
L
Laura GRAU MERCIER, MD
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