Actively Recruiting
Diagnostic and Prognostic Biomarkers of Idiopathic Intracranial Hypertension
Led by Danish Headache Center · Updated on 2023-03-07
300
Participants Needed
2
Research Sites
484 weeks
Total Duration
On this page
Sponsors
D
Danish Headache Center
Lead Sponsor
O
Odense University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, primarily affecting overweight females of childbearing age. Typically, patients experience headache and visual symptoms due to increased intracranial pressure (ICP) and papilledema. The diagnosis is difficult, and outcomes vary from no sequelae to blindness or chronic headaches. No clear prognostic indicators exist. Treatment consists of medication, weight loss, and possibly surgical intervention.There is an unmet need of defining biomarkers with prognostic or diagnostic value and defining predictors of a poor outcome. This project is a prospective, population-based cohort study including clinical data and a biobank (blood samples and cerebrospinal fluid). The investigator's primary aim is to identify biomarkers of diagnostic or prognostic value and to create a clinical IIH database. The clinical database will answer questions about patient characteristics at baseline and during follow-up, identify predictors of outcome, and help create a standardized programme for follow-up and
CONDITIONS
Official Title
Diagnostic and Prognostic Biomarkers of Idiopathic Intracranial Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to and willing to provide informed consent
- More than 18 years of age
- Suspicion of IIH (based on clinical evaluation by neurologist or opthalmologist)
You will not qualify if you...
- Unable to consent (e.g., language barrier, mental retardation)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
The Danish Headache Center, Department of Neurology, Rigshospitalet-Glostrup
Copenhagen, Glostrup, Denmark, 2600
Actively Recruiting
2
Odense University Hospital, Department of Neurology
Odense, Region Syddanmark, Denmark, 5000
Actively Recruiting
Research Team
J
Johanne Severinsen, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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