Actively Recruiting
Diagnostic and Prognostic Markers of Endometriosis in Menstrual Blood
Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2026-04-16
250
Participants Needed
1
Research Sites
138 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to identify diagnostic and prognostic biomarkers for endometriosis using menstrual blood, an easily accessible yet overlooked biological fluid in women of reproductive age, affected or not by endometriosis The main questions it aims to answer are: * are there relevant differences in the menstrual blood of women affected by endometriosis compared to women without endometriosis? * do some of these differences disappear or lessen when the disease is treated by surgery? Participants will answer questions relevant to endometriosis and provide menstrual blood 1 to 3 times (self-collected with a menstrual cup). A subgroup of participants affected by endometriosis that will undergo surgery for their regular care will provide menstrual blood before and after their surgery. Researchers will compare the menstrual blood of women with and without endometriosis, and before and after surgery to see if they can identify significant differences.
CONDITIONS
Official Title
Diagnostic and Prognostic Markers of Endometriosis in Menstrual Blood
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 to 45 years
- Currently having menstrual periods
- Have given written consent to participate
- Have previously used a menstrual cup for menstrual hygiene
- Reside or work in Ile de France (Paris Metropolitan area, France)
- For women with endometriosis: diagnosis confirmed by surgery or imaging (ultrasound and/or MRI)
- For women with endometriosis: presence of one or more painful symptoms greater than 3 on a visual scale (dysmenorrhea, dyspareunia, chronic pelvic pain) and/or infertility
- For surgery subgroup: planned surgery within the next 3 months
- For women without endometriosis: painful symptoms less than or equal to 3 on a visual scale (dysmenorrhea, dyspareunia, chronic pelvic pain)
- For women without endometriosis: no intense period pain in adolescence that required medication or caused school absenteeism
You will not qualify if you...
- Autoimmune diseases
- Chronic diseases other than endometriosis such as diabetes or hypertension
- Being under judicial safeguard measures
- Known infectious diseases such as HIV or hepatitis B virus
- History of menstrual toxic shock syndrome
- For women with endometriosis: endometriosis surgery within the last 3 months
AI-Screening
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Trial Site Locations
Total: 1 location
1
Hopital Cochin
Paris, France
Actively Recruiting
Research Team
L
Ludivine Doridot
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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