Actively Recruiting
Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts
Led by Johns Hopkins University · Updated on 2026-03-02
5000
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying pancreatic cysts, which are often found unexpectedly during imaging scans like CT and MRI. This research aims to understand how these cysts develop over time and to create a reliable method to distinguish between types of cysts, especially identifying those that might be cancerous or pre-cancerous. The study focuses on improving diagnosis by combining clinical information, imaging results, and biomarker data to better predict cyst types and risks. Participants will be observed without receiving any experimental treatments, as this is an observational study. The research involves collecting and analyzing clinical details, imaging scans, and biomarkers from patients with pancreatic cysts. The goal is to develop and validate a diagnostic model that helps doctors decide which cysts need more aggressive monitoring or treatment and which may not. During the study, participants will undergo regular assessments, including medical history reviews and imaging tests, to track the progression of their pancreatic cysts. Researchers will review patient charts over a 15-year period to evaluate the usefulness of the new diagnostic approach called Compcyst. The study includes ongoing monitoring to understand cyst behavior and improve patient management over time.
CONDITIONS
Brief Title
Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients age 18 years and older
- Referred for assessment of a pancreatic cyst
You will not qualify if you...
- Medically ill patients with American Society of Anesthesiologists class 4 or greater
- Inability to provide informed consent
- Pregnancy or lactation
Research Team
E
Elham Afghani, MD MPH
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