Actively Recruiting
Diaphragmatic Function as a Biomarker
Led by RWTH Aachen University · Updated on 2026-01-28
800
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory diseases are still poorly understood. Diaphragm dysfunction might be highly prevalent in patients with dyspnea and respiratory diseases. The association of diaphragm function and potential prognostic significance in patients with respiratory diseases has not yet been investigated.
CONDITIONS
Official Title
Diaphragmatic Function as a Biomarker
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient has one of the following lung diseases: COPD, bronchial asthma, pulmonary fibrosis, pulmonary hypertension
- Is 18 years or older
- Is mentally and physically able to understand the study and to follow instructions
- Is legally competent
- Signed declaration of consent
You will not qualify if you...
- Body mass index (BMI) greater than 35
- Current treatments or past diseases that could affect study evaluation
- Expected lack of willingness to actively participate in study measures
- Alcohol or drug abuse
- Disc herniation or prolapse
- Epilepsy
- Wheelchair bound
- In custody due to official or court order
- In a dependent or employment relationship with the investigator or their deputy
- Emergency inpatient hospital stay within 4 weeks before study examinations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
RWTH Aachen University Hospital
Aachen, North Rhine-Westphalia, Germany, 52074
Actively Recruiting
Research Team
J
Jens Spiesshoefer, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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