Actively Recruiting
Diaphragmatic Function and Respiratory Drive in OSA and COPD
Led by Nanjing Medical University · Updated on 2025-06-25
80
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This cross-sectional observational study aims to assess the diaphragmatic morphofunction and respiratory drive characteristics among patients with obstructive sleep apnea (OSA), chronic obstructive pulmonary disease (COPD), overlap syndrome (OS), and healthy controls. Using ultrasound imaging and surface diaphragm electromyography (EMGdi), the study will explore group differences in diaphragmatic morphology, function, and respiratory drive indicators, and evaluate their clinical significance in disease differentiation and severity assessment.
CONDITIONS
Official Title
Diaphragmatic Function and Respiratory Drive in OSA and COPD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged between 18 and 80 years
- Diagnosed obstructive sleep apnea with AHI 6 5 events/hour for OSA group
- Diagnosed chronic obstructive pulmonary disease based on GOLD guidelines for COPD group
- Diagnosed both OSA (AHI 6 5) and COPD for overlap group
- Healthy volunteers with no known respiratory diseases or sleep disorders for control group
- Ability and willingness to provide informed consent
You will not qualify if you...
- Severe cardiovascular diseases such as unstable angina or heart failure NYHA III/IV
- Severe liver or kidney failure
- Neuromuscular diseases affecting breathing muscles
- Recent upper airway or chest surgery within 3 months
- Pregnancy or breastfeeding
- Inability to complete assessments due to cognitive impairment or poor cooperation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China, 210029
Actively Recruiting
Research Team
D
Ding Ning, doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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