Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID06629610

A Community-led Intervention (DAiLY) Promoting a Heart-healthy Diet and Active Lifestyle: The Yup'ik Way

Led by Oregon Health and Science University · Updated on 2025-05-07

368

Participants Needed

2

Research Sites

17 weeks

Total Duration

On this page

Sponsors

O

Oregon Health and Science University

Lead Sponsor

J

Johns Hopkins Bloomberg School of Public Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

Heart disease is a leading cause of death among Yup'ik Alaska Native people, with risk factors linked to changes in diet and physical activity over the past 60 years. This research aims to evaluate the effectiveness of the Diet and Active Lifestyle - Yuuyaraq (DAiLY) intervention, which is grounded in Yup'ik cultural values and Indigenous Food Sovereignty, to reduce heart disease risk by promoting healthier eating and more active lifestyles. The DAiLY intervention lasts two years and includes three main components: home-based workshops led by community members to increase knowledge about healthy traditional and store-bought foods and physical activity; modifications in local food stores to improve access to affordable healthy foods through promotions and education; and community events such as traditional dance, sports, and berry festivals to encourage physical activity. These components are supported by social media, text messaging, and visual materials, with participants using Fitbits to track activity. Participants will be involved in workshops, community events, and store promotions while researchers collect data through fasting blood samples, physical measurements, activity monitors, and questionnaires on diet and wellness. The study measures changes in heart disease risk using a continuous metabolic syndrome score over two years and also evaluates participant satisfaction, program reach, and community-level outcomes like food access and physical activity opportunities. Results will be shared with communities, and all intervention materials will be freely available after the trial.

CONDITIONS

Brief Title

Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Self-identify as Yup'ik Alaska Native
  • Live in a participating Yup'ik community
  • Plan to remain in the community for the 24-month intervention period
  • Be 18 years of age or older
  • Community Tribal governments provide letters of support for the intervention study
  • Community agrees to participate in Community Based Participatory Research activities
  • Food stores located within the participating community, commonly used by residents, and able to support intervention components
Not Eligible

You will not qualify if you...

  • Currently pregnant
  • Plan to move out of the community within the next 24 months
  • Under 18 years of age
  • Participated in the pilot intervention before

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 2 years

Participants take part in a 2-year intervention including home-based workshops delivered by community members to increase knowledge and skills related to food choices and physical activity. The intervention also involves food store modifications to increase access to healthy foods and community-wide physical activity promotion through traditional activities and events, supported by social media and Fitbit tracking.

Ongoing community activities and workshops throughout the intervention period

Trial Site Locations

Total: 2 locations

1

Yukon-Kuskokwim Health Corporation

Bethel, Alaska, United States, 99559

Actively Recruiting

2

Oregon Health and Science University

Portland, Oregon, United States, 97239-3098

Not Yet Recruiting

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Research Team

B

Bert B Boyer, PhD

J

Joel Gittelsohn, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Frequently Asked Questions

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Published Research Related To This Trial

A stable isotope biomarker of marine food intake captures associations between n-3 fatty acid intake and chronic disease risk in a Yup'ik study population, and detects new associations with blood pressure and adiponectin.

Diane M O'Brien, Alan R Kristal, Sarah H Nash...

https://pubmed.ncbi.nlm.nih.gov/24598880

Yup'ik culture and context in Southwest Alaska: community member perspectives of tradition, social change, and prevention.

Paula Ayunerak, Deborah Alstrom, Charles Moses...

https://pubmed.ncbi.nlm.nih.gov/24771075

Conceptions of wellness among the Yup'ik of the Yukon-Kuskokwim Delta: the vitality of social and natural connection.

Christopher Wolsko, Cecile Lardon, Scarlett Hopkins...

https://pubmed.ncbi.nlm.nih.gov/17060033

Examining Indigenous food sovereignty as a conceptual framework for health in two urban communities in Northern Ontario, Canada.

Lana Ray, Kristin Burnett, Anita Cameron...

https://pubmed.ncbi.nlm.nih.gov/30964405

Reprint of: Blood Sugar Regulation for Cardiovascular Health Promotion and Disease Prevention: JACC Health Promotion Series.

Peter E H Schwarz, Patrick Timpel, Lorenz Harst...

https://pubmed.ncbi.nlm.nih.gov/30522637

Association Between Dietary Factors and Mortality From Heart Disease, Stroke, and Type 2 Diabetes in the United States.

Renata Micha, Jose L Peñalvo, Frederick Cudhea...

https://pubmed.ncbi.nlm.nih.gov/28267855

Stable nitrogen and carbon isotope ratios indicate traditional and market food intake in an indigenous circumpolar population.

Sarah H Nash, Andrea Bersamin, Alan R Kristal...

https://pubmed.ncbi.nlm.nih.gov/22157543

Westernizing diets influence fat intake, red blood cell fatty acid composition, and health in remote Alaskan Native communities in the center for Alaska Native health study.

Andrea Bersamin, Bret R Luick, Irena B King...

https://pubmed.ncbi.nlm.nih.gov/18237575

Obesity-Associated Dyslipidemia Is Moderated by Habitual Intake of Marine-Derived n-3 Polyunsaturated Fatty Acids in Yup'ik Alaska Native People: A Cross-Sectional Mediation-Moderation Analysis.

Bert B Boyer, Howard W Wiener, Scarlett E Hopkins...

https://pubmed.ncbi.nlm.nih.gov/36913463