Actively Recruiting
Diet and Cognitive Training in Hematologic Cancer Survivors
Led by University of Alabama at Birmingham · Updated on 2025-12-17
80
Participants Needed
1
Research Sites
231 weeks
Total Duration
On this page
Sponsors
U
University of Alabama at Birmingham
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to examine feasibility of a cognitive intervention program in blood cancer survivors. The main questions it aims to answer are: * is it feasible to combine a ketogenic diet supplementation and online cognitive training in an intervention program * will patients using the combined intervention program have improved cognitive functioning compared to those who don't use it * how long will the intervention programs effects last Participants randomized to the intervention arm will consume an exogenous ketogenic supplementation and use an online cognitive training program for 12 weeks, while waitlist arm functions as a control group and will receive the online cognitive training only after a wait period of 12 weeks. Researchers will compare the intervention and waitlist control groups to see if the intervention improves cognitive functioning.
CONDITIONS
Official Title
Diet and Cognitive Training in Hematologic Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult with hematologic malignancy diagnosed at age 6521 years
- Outpatient at least 3 months from completion of blood or marrow transplant (BMT) or at least 6 months from diagnosis for patients not treated with BMT
- Evidence of mild-to-moderate cognitive impairment using either the Modified Telephone Interview for Mild Cognitive Impairment (TICS-M) or PROMIS 8a short form raw score = 19 -37
- Have daily access to an internet-connected home computer
- Can fluently read and write in English
- Can understand and sign the study-specific Informed Consent Form
You will not qualify if you...
- History of pre-existing neurological disorder or documented major psychiatric disorder
- Significant auditory, visual, or motor impairments
- History of color blindness
- Participated in neuropsychological intervention within the past 6 months
- Evidence of active chronic graft vs. host disease (GvHD) for allogeneic BMT
- History of pre-existing metabolic disease
- Allergies to soy or milk
- Body Mass Index (BMI) 6420
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35233
Actively Recruiting
Research Team
N
Noha M Sharafeldin, MD, MSc, PhD
CONTACT
L
Lindsey Hageman, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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