Actively Recruiting
Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease
Led by Weill Medical College of Cornell University · Updated on 2026-02-27
40
Participants Needed
1
Research Sites
452 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will assess the impact of time-restricted eating (8 hours of eating each day) with standard of care lifestyle recommendations (hypocaloric, Mediterranean diet and 30 minutes of exercise on at least 5 days/week) on the degree of fat in the liver as measured by magnetic resonance imaging.
CONDITIONS
Official Title
Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to less than 65 years old
- Provide signed written informed consent and agree to follow the study plan
- Body mass index (BMI) greater than 25 kg/m²
- Liver fat content of at least 10% measured by MRI-PDFF at the start of the study
You will not qualify if you...
- Unclear cause of liver disease
- Other causes of liver fat accumulation
- Other chronic liver diseases including hepatitis B, hepatitis C, drug-induced liver disease, alcoholic liver disease, autoimmune hepatitis, Wilson's disease, hemochromatosis, primary biliary cholangitis, or primary sclerosing cholangitis
- Known or suspected liver cancer
- Significant alcohol use in the past 5 years (more than 30g per day for men, more than 20g per day for women)
- Cirrhosis or advanced liver fibrosis
- Weight loss of 5% or more in the past 90 days
- Regular fasting for 12 hours or more on most days
- Pregnancy
- Mental instability or inability to consent or follow the study
- Unable to undergo MRI scans
- Unable to safely perform prolonged fasting (such as those on insulin treatment)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Weill Cornell Medicine
New York, New York, United States, 10021
Actively Recruiting
Research Team
S
Sonal Kumar, MD
CONTACT
L
Lara Phipps
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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