Actively Recruiting
Diet Synergy in Muscle Protein Synthesis
Led by University of Illinois at Urbana-Champaign · Updated on 2026-05-01
15
Participants Needed
2
Research Sites
139 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise, participants will ingest either 1 medium russet potato with skins and 2 ounce-equivalent lean ground beef combination (274 kcals, 19.3 g protein, 5 g fat, 37 g carbohydrates, and 4 g fiber), 2 slices of white bread and beef combination (262 kcals, 19.8 g protein, 6.8 g fat, 28 g carbohydrates, and 1.8 g fiber) or 2 ounce-equivalent beef (93% lean meat/7% fat; 110 kcals, 14.8 g protein, and 5 g fat). Repeated blood and muscle biopsies will be collected to determine whole body leucine kinetics, amino acid concentrations, anabolic signaling and myofibrillar protein synthesis rates during the trials.
CONDITIONS
Official Title
Diet Synergy in Muscle Protein Synthesis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 19 to 40 years
- Pre-menopausal females
- Recreationally active individuals
- Stable weight for the prior 6 months
You will not qualify if you...
- Age outside the 19 to 40 year range
- Pregnancy
- Irregular menstrual cycles (around 21 or 35 days)
- Previous participation in research using L-[1-13C] leucine and L-[ring-2H5] phenylalanine
- Participation in other ongoing research that interferes with this study (e.g., conflicting diet or activity interventions)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Louise Freer Hall
Urbana, Illinois, United States, 61801
Not Yet Recruiting
2
Louise Freer Hall
Urbana, Illinois, United States, 61801
Actively Recruiting
Research Team
N
Nicholas A Burd (Full Professor), PhD
CONTACT
C
Calvin Chen, PhD Student
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
3
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