New directions in dietary studies and heart disease: the National Heart, Lung and Blood Institute sponsored Multicenter Study of Diet Effects on Lipoproteins and Thrombogenic Activity.
H N Ginsberg
https://pubmed.ncbi.nlm.nih.gov/7598013Completed
Phase 3
Age: 18Years - 75Years
All Genders
ID00000538
Led by University of North Carolina, Chapel Hill · Updated on 2024-02-22
189
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of North Carolina, Chapel Hill
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To evaluate the effects of carefully controlled diets on lipoproteins and clotting factors in different demographic groups.
CONDITIONS
Official Title
Dietary Effects on Lipoproteins and Thrombogenic Activity
Who Can Participate
Age: 18Years - 75Years
All Genders
Eligibility Criteria
You may qualify if you...
Men and women with low HDL and/or high triglyceride levels and/or high insulin levels.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
Diet design for a multicenter controlled feeding trial: the DELTA program. Delta Research Group.
B H Dennis, P Stewart, C H Wang...
https://pubmed.ncbi.nlm.nih.gov/9664917ApoE genotype does not predict lipid response to changes in dietary saturated fatty acids in a heterogeneous normolipidemic population. The DELTA Research Group. Dietary Effects on Lipoproteins and Thrombogenic Activity.
M Lefevre, H N Ginsberg, P M Kris-Etherton...
https://pubmed.ncbi.nlm.nih.gov/9409276Variation of lipids and lipoproteins in premenopausal women compared with men and postmenopausal women. DELTA (Dietary Effects on Lipoproteins and Thrombogenic Activity) Investigators.
R G Reed, P Kris-Etherton, P W Stewart...
https://pubmed.ncbi.nlm.nih.gov/11016887Effects of reducing dietary saturated fatty acids on plasma lipids and lipoproteins in healthy subjects: the DELTA Study, protocol 1.
H N Ginsberg, P Kris-Etherton, B Dennis...
https://pubmed.ncbi.nlm.nih.gov/9514413Reducing saturated fat intake is associated with increased levels of LDL receptors on mononuclear cells in healthy men and women.
V A Mustad, T D Etherton, A D Cooper...
https://pubmed.ncbi.nlm.nih.gov/9101427HDL-subpopulation patterns in response to reductions in dietary total and saturated fat intakes in healthy subjects.
L Berglund, E H Oliver, N Fontanez...
https://pubmed.ncbi.nlm.nih.gov/10584043High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations.
P M Kris-Etherton, T A Pearson, Y Wan...
https://pubmed.ncbi.nlm.nih.gov/10584045Effect of alpha-fetoprotein on arachidonic acid metabolism in a human T-cell line.
C Aussel, M Fehlmann
https://pubmed.ncbi.nlm.nih.gov/2438210The Type and Amount of Dietary Fat Affect Plasma Factor VIIc, Fibrinogen, and PAI-1 in Healthy Individuals and Individuals at High Cardiovascular Disease Risk: 2 Randomized Controlled Trials.
Penny M Kris-Etherton, Paul W Stewart, Henry N Ginsberg...
https://pubmed.ncbi.nlm.nih.gov/32492148