Actively Recruiting
Dietary Inflammatory Index and Periodontal Status in Obese Patients
Led by Recep Tayyip Erdogan University Training and Research Hospital · Updated on 2025-12-17
200
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study aimed to investigate the effect of nutrition on periodontal status in individuals diagnosed with obesity and without any other systemic disease, and to investigate the relationship between DII and periodontal disease risk. A total of 200 participants will be included in the study. Participants' overall daily Dietary Inflammatory Index (DII) scores will be calculated. The obtained scores will be divided into four groups, from low to high: Q1 (n=50), Q2 (n=50), Q3 (n=50), and Q4 (n=50). According to the DII, groups Q1 and Q2, which include lower scores, represent individuals on an anti-inflammatory diet, while groups Q3 and Q4, which include higher scores, represent individuals on a pro-inflammatory diet. Interleukin (IL)-1β, IL-10, total oxidant status (TOS), and total antioxidant status (TAS) were collected from gingival crevicular fluid (GCF) and serum samples. The levels of biomarkers such as malondialdehyde (MDA), glutathione (GSH), leptin, adiponectin, tumor necrosis factor (TNF)-α and C-reactive protein (CRP) from serum samples alone will be analyzed by ELISA method at the Recep Tayyip Erdoğan University Medical Biochemistry Laboratory.
CONDITIONS
Official Title
Dietary Inflammatory Index and Periodontal Status in Obese Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with obesity (BMI > 30 kg/m2 or waist circumference > 100 cm for men and > 90 cm for women)
- No systemic diseases other than obesity, such as cardiovascular disease, chronic kidney disease, Type 1 or Type 2 diabetes, or hypertension (>130/85 mmHg)
- Age between 18 and 65 years
- Do not smoke or consume alcohol
- Have not used anti-inflammatory medications in the last 3 months or antibiotics or systemic corticosteroids in the last 6 months
- Not pregnant or lactating
- Have not received periodontal treatment in the last 6 months
- Have not received nutritional advice in the last 3 months
You will not qualify if you...
- Not diagnosed with obesity
- Have systemic diseases other than obesity, such as cardiovascular disease, chronic kidney disease, Type 1 or Type 2 diabetes, or hypertension (>130/85 mmHg)
- Younger than 18 or older than 65 years
- Smoke or consume alcohol
- Have used anti-inflammatory drugs in the last 3 months or antibiotics or systemic corticosteroids in the last 6 months
- Pregnant or lactating
- Received periodontal treatment in the last 6 months
- Received nutritional advice in the last 3 months
AI-Screening
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Trial Site Locations
Total: 1 location
1
Recep Tayyip Erdoğan University
Rize, Turkey (Türkiye), 53020
Actively Recruiting
Research Team
H
Hatice Yemenoglu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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