Study of a Healthy Dietary Pattern to Reduce Atopic Dermatitis Severity in Adults with Allergic Conditions

What this Trial Is About

Researchers are exploring how diet affects atopic dermatitis AD, a chronic inflammatory skin condition that often starts early and can impact quality of life, sleep, and mental well-being. This study aims to understand whether a healthy dietary pattern, adapted to local guidelines, can reduce AD severity in young adults. The trial focuses on whole-diet changes rather than single nutrients and addresses a gap in research among Asian adult populations. Participants are randomly assigned to one of two groups for a 2-month period. The intervention group receives daily bento-style meals for lunch and dinner, prepared by a licensed catering service, featuring whole grains, lean proteins, fruits, vegetables, and healthy fats. The control group continues with their usual diet without receiving meals or nutritional advice. After the intervention, a follow-up occurs one month later to assess lasting effects. Throughout the study, participants undergo assessments at the start, after 2 months, and at 1 month post-intervention. Researchers measure AD severity using SCORAD scores, skin barrier function, quality of life specific to dermatology, medication use, body measurements, blood pressure, blood lipid profiles, inflammatory markers, and gut microbiota composition. The study tracks adherence and changes to understand the diets impact on AD and overall health.

Dietary Intervention on Atopy