Actively Recruiting
Dietary Intervention on Atopy
Led by National University of Singapore · Updated on 2026-04-01
110
Participants Needed
1
Research Sites
190 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Diet is a key determinant of overall health, with growing evidence associating dietary patterns with allergic diseases. Among these, atopic dermatitis (AD) is of particular interest as it often represents the earliest manifestation of the atopic triad. Investigating dietary interventions in AD therefore provides a relevant model to better understand how diet may influence the onset and progression of allergic disease more broadly.
CONDITIONS
Official Title
Dietary Intervention on Atopy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Presence of current, mild-to-moderate atopic dermatitis or eczema at flexural areas
- Age between 21 and 65 years at screening
- English-literate and able to give informed consent in English
- Residing in Singapore and not travelling outside Singapore during the study
- Reliable and willing to follow study procedures and available for full study duration
- Non-smoker (tobacco and e-cigarette)
- Non-drinker (no regular or frequent alcohol consumption)
- Generally healthy with no pre-existing medical conditions like diabetes, hypertension, cancer, blood disorders, degenerative, liver, autoimmune, immune, renal diseases, or psychiatric conditions
- No food allergies to test foods
- No needle phobia
- Willing to follow instructions on the use of moisturisers, cosmetics, and topical creams throughout the study
You will not qualify if you...
- Participation in other research studies concurrently
- Pregnancy or lactation
- Known or ongoing psychiatric disorders within 3 years
- Known severe nutritional deficiency
- Vegetarian or vegan diet due to inclusion of meat in diet
- Significant dietary change in past 12 months
- Pre-existing dietary restrictions interfering with adherence to whole diet meal
- Regular use of strong medications, therapies, or alternative medicines
- Regular nutritional supplement use in past 12 months
- Regular use of oral contraceptive pills or steroid hormones
- Antibiotic use in past 2 months
- Long-term hospitalisation or surgery within 6 months before study enrolment
- Significant weight change (+/- 5%) in past month
- History of bleeding disorders or coagulopathy
- Blood donation of more than 500 mL within 4 weeks before enrolment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National University of Singapore
Singapore, Singapore, Singapore, 118177
Actively Recruiting
Research Team
M
Mei Hui Liu, PhD
CONTACT
J
Jun Jie Lim, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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