Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05709600

Dietary Interventions During Living Kidney Donations

Led by University of Cologne · Updated on 2026-04-30

80

Participants Needed

1

Research Sites

230 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney biopsy samples in patients preconditioned by different dietary regimes (fasting mimicking diet vs. ketogenic diet vs. dietary restriction of sulfur containing amino acids vs. control patients)

CONDITIONS

Official Title

Dietary Interventions During Living Kidney Donations

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age
  • Planned living kidney transplantation (both donor and recipient are eligible)
  • Written informed consent
Not Eligible

You will not qualify if you...

  • Vegetarian lifestyle
  • Body mass index (BMI) below 18.5 kg/m2
  • Calorie-reduced diet within the preceding four weeks
  • Underlying wasting syndrome
  • Contraindication for enteral nutrition
  • Known allergy or intolerance to ingredients of the diet used
  • Pregnancy
  • Breastfeeding
  • Absence of safe contraceptive measures or non-occurrence of menopause (in women)
  • Participation in other interventional trials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department II of Internal Medicine, Center for Molecular Medicine Cologne (CMMC), University Hospital of Cologne

Cologne, Germany, 50931

Actively Recruiting

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Research Team

F

Felix Köhler, MD

CONTACT

R

Roman-Ulrich Müller, Prof. MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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