Actively Recruiting
Dietary Potassium Liberalization in Pre-Dialysis Patients
Led by University of Manitoba · Updated on 2026-01-16
30
Participants Needed
2
Research Sites
123 weeks
Total Duration
On this page
Sponsors
U
University of Manitoba
Lead Sponsor
D
Dalhousie University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study will look at the impact of the potassium content in fruits and vegetables, on serum potassium concentrations in people with Chronic Kidney Disease (CKD) using a randomized crossover design. Participants will receive home delivery of fruit and vegetables with either higher or lower potassium content in a random order. Clinical chemistry markers from blood and urine samples, blood pressure, physical functioning and health related quality of life will be assessed throughout the duration of the trial. This study will also measure their physical functioning, using a chair stand test. The results of this study could change the dietary recommendations for people with CKD related to potassium.
CONDITIONS
Official Title
Dietary Potassium Liberalization in Pre-Dialysis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female, aged 18 years or above
- Estimated glomerular filtration rate between 15 and 45 ml/min/1.73m2
- Serum potassium concentration between 4.5 and 5.5 milliequivalent (mEq)/L
- Hemoglobin A1c 11%
- Systolic and diastolic blood pressure <160/100 mmHg
- Registered in the multidisciplinary nephrology clinic in Winnipeg
- Able to communicate in English and provide written informed consent
You will not qualify if you...
- Serum potassium concentration > 5.6 mEq/L, anuria, dialysis, or acute kidney injury failure in the 6 months prior to screening
- Chronic obstructive pulmonary disease requiring oxygen
- New York Heart Association Class 3-4 heart symptoms or heart, liver, or renal transplant
- Myocardial infarction or stroke within the last 6 months
- Unable to consume study treatments or control due to swallowing or gastrointestinal issues
- Currently on potassium binding therapy
- Any medical condition, uncontrolled systemic disease, or concurrent illness that would reduce study compliance or participant safety
- Female participant who is pregnant or lactating
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Seven Oaks General Hospital Chronic Disease Innovation Centre
Winnipeg, Manitoba, Canada, R2V 3M3
Actively Recruiting
2
Health Sciences Centre
Winnipeg, Manitoba, Canada, R3A 1R9
Actively Recruiting
Research Team
D
Dylan Mackay, PhD
CONTACT
R
Rebecca Mollard, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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