Actively Recruiting
Differences in Extracellular Vesicles From Adipose Tissue of Individuals With Obesity.
Led by Hasselt University · Updated on 2025-09-15
150
Participants Needed
1
Research Sites
184 weeks
Total Duration
On this page
Sponsors
H
Hasselt University
Lead Sponsor
R
Research Foundation Flanders
Collaborating Sponsor
AI-Summary
What this Trial Is About
Our society is characterized by a strong increase in the prevalence of obesity, which often causes the development of cardiovascular and metabolic diseases such as type 2 diabetes. The way(s) obesity is responsible for these diseases, is still insufficiently understood. This study therefore examines the content of human fat tissue storage location- and cell type-specific extracellular vesicles (EVs) in lean and obese individuals, and the possible connection with sex, insulin sensitivity, and the blood-brain barrier.
CONDITIONS
Official Title
Differences in Extracellular Vesicles From Adipose Tissue of Individuals With Obesity.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Caucasian adults with obesity with a body mass index (BMI) of at least 35 kg/m² scheduled for their first bariatric surgery
- Male and female ratio in the study will be 1:1
- Minimal knowledge of Dutch to read and understand informed consent
- Caucasian adults without obesity with a BMI between 18 and 24.9 kg/m² scheduled for abdominal surgery
- Female only for the lean group
- Minimal knowledge of Dutch to read and understand informed consent
You will not qualify if you...
- Smoking and/or drug abuse
- Cardiovascular diseases including implanted aids like pacemaker or defibrillator
- Lung diseases
- Kidney diseases
- Brain and/or nerve diseases
- Malignant diseases such as cancer
- For lean participants, endocrine diseases like type 2 diabetes are excluded
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ziekenhuis Oost-Limburg
Genk, Limburg, Belgium, 3600
Actively Recruiting
Research Team
L
Lisa Mennens
CONTACT
K
Kenneth Verboven
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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