Actively Recruiting
Randomized Trial Comparing Postoperative Symptoms With Four Ureteral Stent Types After Laser Lithotripsy of Kidney and Ureteral Stones
Led by University of Wisconsin, Madison · Updated on 2026-06-08
272
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a randomized controlled trial to compare postoperative symptoms related to four types of ureteral stents used after ureteroscopy with laser lithotripsy for treating upper urinary tract stones. The study will assess differences in symptom scores among 6Fr Percuflex, 6Fr Tria, 4.8Fr Percuflex, and 4.8Fr Tria ureteral stents. A total of 272 participants will be enrolled and followed for up to approximately 10 weeks. Participants will undergo surgery with placement of one of the four ureteral stents. The trial includes three clinic visits: a pre-operative visit, a visit for stent removal 1-2 weeks after surgery, and a postoperative visit 3-6 weeks after surgery. The stents differ in size and coating properties, with the Tria stents designed to soften at body temperature and resist mineral buildup. Researchers will collect data including patient demographics, medical history, and physician assessments. Participants will complete the Ureteral Stent Symptom Questionnaire (USSQ) twice to measure urinary symptoms, pain, general health, work performance, and sexual matters at stent removal and post-stent removal visits. Additional outcomes include quality of life measured by WisQOL, emergency room visits, unscheduled clinic follow-ups, extra prescriptions for stent symptoms, stent complications by imaging, and physician evaluations. These assessments will help compare the patient experience and safety of each stent type throughout the study period.
CONDITIONS
Brief Title
Differences in Postoperative Symptoms With Four Ureteral Stents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with kidney or ureteral stones who need endoscopic treatment and ureteral stent placement in an outpatient operating room
- Age between 18 and 89 years
- Able to provide informed consent and understand study procedures
You will not qualify if you...
- Pregnant patients
- Patients with kidney transplants
- Patients with irreversible blood clotting disorders
- Patients with known ureteral stricture disease
- Non-English speakers, vulnerable patients lacking decision-making capacity, prisoners, or adults unable to consent
- Patients with planned staged procedures
- Patients who had a stent placed before surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo laser lithotripsy surgery and ureteral stent placement with one of four stent types.
1 visit (in-person surgery)
Duration - 1 to 2 weeks
Participants have their stent removed 1-2 weeks after surgery and complete symptom questionnaires. This visit follows standard care.
1 visit (in-person stent removal)
Duration - 3 to 6 weeks
Participants complete a final post-operative visit 3-6 weeks after surgery to assess recovery and symptoms using questionnaires. This visit follows standard care.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, United States, 53792
Actively Recruiting
Research Team
S
Shuang Li
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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