Actively Recruiting
Different Cycles of Neoadjuvant PD-1 Blockades + Chemotherapy for Advanced Gastric Cancer
Led by Chinese PLA General Hospital · Updated on 2025-01-29
300
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to analyze the impact of different durations of neoadjuvant PD-1 inhibitor combined with chemotherapy on tumor regression and safety in patients with advanced gastric cancer. The main questions it aims to answer are: * Does the duration of neoadjuvant treatment influence tumor regression grading (TRG)? * How does treatment duration affect perioperative safety and clinical outcomes? Participants who have previously undergone neoadjuvant PD-1 inhibitor combined with chemotherapy followed by surgery as part of their routine medical care will have their clinical data retrospectively reviewed and analyzed.
CONDITIONS
Official Title
Different Cycles of Neoadjuvant PD-1 Blockades + Chemotherapy for Advanced Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Non-bedridden patients aged 18-90 years
- Histologically confirmed gastric or gastroesophageal junction adenocarcinoma by biopsy
- Evaluated as resectable advanced gastric cancer via CT, MRI, or laparoscopic exploration
- No prior anti-tumor treatments such as chemotherapy, radiotherapy, or immunotherapy
- No history of other malignancies within the past 5 years
- Received at least one cycle of PD-1 inhibitor combined with chemotherapy preoperatively
- Underwent radical gastrectomy after neoadjuvant therapy
- No severe underlying diseases
You will not qualify if you...
- Incomplete or inaccessible clinical and pathological data
- Postoperative pathology confirming non-gastric or non-gastroesophageal junction adenocarcinoma
- Distant metastases present prior to treatment
- Concurrent diagnosis of other malignancies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Chinese PLA General Hospital
Beijing, China, 100853
Actively Recruiting
Research Team
X
Xinxin Wang
CONTACT
S
Shuo Li
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here