Actively Recruiting

Phase Not Applicable
Age: 4Months - 2Years
All Genders
Healthy Volunteers
ID05989438

Analysis of the Impact of Different Intervention Models on the Neuropsychomotor Development of Premature Infants Based on the ICF Biopsychosocial Model

Led by Federal University of Health Science of Porto Alegre · Updated on 2025-06-25

60

Participants Needed

1

Research Sites

32 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Prematurity is an important risk factor for delays in neuropsychomotor development, which can affect a baby's functional abilities. This research aims to analyze how different intervention models based on the International Classification of Functioning (ICF) biopsychosocial model impact the neuropsychomotor development of premature infants. The study focuses on babies born before 37 weeks of gestation, assessing their development from corrected ages of 4 months up to 24 months. Participants are divided into two groups: one receiving only guidance for families through monthly phone calls and weekly reminders, and another receiving both professional stimulation sessions and family guidance. The professional stimulation involves sessions lasting about 50 minutes with exercises in various positions tailored to the baby's neuropsychomotor development and corrected age, with frequency depending on prematurity level. Both groups receive printed guides and age-appropriate toys to support stimulation at home. Assessments occur at 4, 8, 12, and 24 months corrected age. Throughout the study, families will regularly stimulate their babies at home and report frequency. Evaluations include neuropsychomotor development measured by the Bayley Infant and Toddler Development Scales, cognitive assessment with the Montreal Cognitive Assessment, home environment quality, quality of life, and socioeconomic factors. Researchers will maintain contact via phone for guidance and support. The total participation duration extends to 24 months corrected age, with safety and progress closely monitored.

CONDITIONS

Brief Title

Different Intervention Models of Premature Infants Based on the ICF Biopsychosocial Model

Who Can Participate

Age: 4Months - 2Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Gestational age less than 37 weeks
  • Corrected age between 4 and 12 months (with a one and a half month window) and at 24 months (four months window)
  • Babies registered at the High Risk Outpatient Clinic of the UCS Clinical Center
  • Authorization from the child's legal guardian by signing the Free and Informed Consent Form (TCLE)
Not Eligible

You will not qualify if you...

  • Not meeting the inclusion criteria
  • Having neurological diseases
  • Presence of acute diseases such as pneumonia, bronchiolitis, or trauma
  • Musculoskeletal alterations
  • Genetic syndromes or undergoing genetic investigation
  • Heart diseases requiring surgical intervention
  • Untreated congenital torticollis
  • Congenital clubfoot
  • Cerebral hemorrhage grade IV
  • Missing first and/or last evaluation
  • Incomplete evaluations
  • Convulsive crises during the study period
  • Participation in other intervention programs

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - From 4 to 12 corrected months

Participants receive either monthly telephone orientations with weekly reminders or professional stimulation sessions combined with family orientations based on the baby's corrected age and degree of prematurity. Families also perform daily stimulation at home following guidance provided.

3 evaluation visits approximately every 4 months and monthly phone contacts; professional stimulation sessions occur 1 to 8 times per month depending on prematurity for the stimulation group

Follow-up

Duration - Up to 24 corrected months

Participants continue to be assessed at 24 months corrected age to evaluate neuropsychomotor development and other outcomes.

1 evaluation visit around 24 months corrected age

Trial Site Locations

Total: 1 location

1

Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)

Porto Alegre, Rio Grande do Sul, Brazil, 90050170

Actively Recruiting

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Research Team

F

Fernanda Cechetti, Full professor

T

Tatiane Paludo, PhD Student

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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