Actively Recruiting
Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions
Led by Shanghai Zhongshan Hospital · Updated on 2024-11-26
20
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study involves collecting paired tumor samples from intrasellar and cavernous sinus regions of 20 invasive pituitary tumor patients, preserving them at -80°C for quality multi-omics analysis. Proteomics and transcriptomics are employed to identify molecular differences, while imaging data (MRI/CT) assesses tumor morphology and invasion. In vitro experiments and mechanistic studies validate key findings, exploring how regional molecular differences affect tumor behavior. Data integration combines multi-omics and imaging features to uncover biomarkers and pathways associated with invasiveness and regional specificity, with statistical analysis ensuring significance and reliability.
CONDITIONS
Official Title
Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 80 years
- Diagnosis of invasive pituitary tumors involving the cavernous sinus
- Signed informed consent forms for donation of biological samples and health-related information
- Willingness to participate in the study
You will not qualify if you...
- Non-invasive pituitary tumors
- Pregnant or breastfeeding
- Other conditions considered unsuitable for participation by the physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
T
Tao Xie
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here