Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
NCT04420702

Diffusion Basis Spectrum Imaging of the Prostate

Led by Washington University School of Medicine · Updated on 2025-07-18

500

Participants Needed

1

Research Sites

378 weeks

Total Duration

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Sponsors

W

Washington University School of Medicine

Lead Sponsor

A

American Cancer Society, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Diffusion Basis Spectrum Imaging (DBSI) represents a potential leap forward in improving prostate cancer early detection: a non-invasive and accurate imaging test for clinically significant prostate cancer.

CONDITIONS

Official Title

Diffusion Basis Spectrum Imaging of the Prostate

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 18 years of age and willing and able to provide informed consent
  • Patients with no prior diagnosis of prostate cancer, planning to undergo prostate biopsy as clinical standard of care
  • Men with elevated PSA and no prior biopsy
  • Men with elevated PSA and a negative prior biopsy
  • Patients with prior prostate cancer diagnosis managed with active surveillance, planning to undergo biopsy as clinical standard of care
Not Eligible

You will not qualify if you...

  • Patients with any clinical contraindication to MRI
  • Patients with metallic implants such as pacemakers or implantable cardioverter-defibrillators
  • Patients with cochlear implants
  • Patients with claustrophobia not relieved with medication
  • Patients unable to lie flat for over 1 hour
  • Patients with prior prostate surgery for prostate cancer (e.g. radical prostatectomy, focal ablation)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Washington University School of Medicine

St Louis, Missouri, United States, 63110

Actively Recruiting

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Research Team

J

Joseph Ippolito, M.D.

CONTACT

A

Alex Klim

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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