Study of Digital Walking Activity Monitoring in Adults with Pulmonary Hypertension Using Wearable Sensors and Follow-Up Assessments

What this Trial Is About

Researchers are investigating how digital mobility outcomes can help monitor treatment and disease progression in adults with pulmonary hypertension, specifically precapillary pulmonary hypertension. The study aims to see if walking behavior measured by digital sensors correlates with pulmonary arterial pressure assessed by right heart catheterization. This observational trial is led by Simon Jger and focuses on real-world walking activity in this patient population. Participants will wear a small accelerometer device on their lower back for one week at a time during three separate periods at diagnosis, then at follow-up visits scheduled by their treating clinician between 3 to 6 months and again between 6 to 12 months. The sensor is waterproof and does not provide feedback or display data directly to patients. Follow-up visits are planned according to clinical care, and participants can choose to receive feedback on their sensor data at the studys end. During the study, researchers will assess the correlation between the digital mobility measurements and pulmonary arterial pressures at baseline and follow-ups. They will also describe daily walking behavior, including the number and duration of walking episodes and step counts, and explore links with cardiac function and disease progression. Participants will be monitored over about a year, with safety and ongoing assessment integrated into their regular clinical visits.

Digital Assessment of Real-World Walking Activity in Pulmonary Hypertension: A Prospective Multicenter Trial