Actively Recruiting
Digital CBT for Insomnia and Depression
Led by University of Rochester · Updated on 2026-05-11
1200
Participants Needed
1
Research Sites
228 weeks
Total Duration
On this page
Sponsors
U
University of Rochester
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions are best for which individuals, and if so, to develop and individualized intervention rule to better match individuals with the treatment that is most likely to lead to the best outcomes. A large randomized trial will be conducted to meet these objectives.
CONDITIONS
Official Title
Digital CBT for Insomnia and Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English-speaking
- U.S. Military Veterans
- Endorse depression with a Patient Health Questionnaire-depression score greater than 10
- Endorse insomnia with an Insomnia Severity Index score greater than 10
You will not qualify if you...
- Currently pregnant
- History of bipolar disorder
- History of psychosis
- Current use of anti-psychotic medications or mood stabilizers (e.g., lithium)
- Current suicidal ideation with active intent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Rochester Sleep Research Laboratory
Rochester, New York, United States, 14642
Actively Recruiting
Research Team
W
Wilfred Pigeon, PhD
CONTACT
M
Michelle Carr, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
5
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