Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT07211867

A Digital Intervention to Decrease Self-Stigma Among Pregnant and Postpartum Women With Substance Use Disorder

Led by Washington University School of Medicine · Updated on 2025-11-26

152

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

Sponsors

W

Washington University School of Medicine

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Digital interventions have the potential to support healthier behaviors among pregnant and postpartum women (PPW) with substance use disorders (SUDs) and may also provide a promising method for reducing their self-stigma. Enhearten is a digital intervention designed to foster adherence to medications for addiction treatment (MAT) while considering the unique needs of PPW, but its effects on self-stigma, treatment retention, and SUD outcomes have not been rigorously tested. The investigators will conduct an individual-level multicenter randomized controlled trial to test the feasibility, acceptability, and efficacy of Enhearten on reducing self-stigma and on improving SUD treatment and recovery outcomes with a stigma-focused ecological momentary intervention (EMI) designed to: 1) screen for feelings of stigma and 2) counteract these vulnerabilities among PPW with SUD via just-in-time interventions.

CONDITIONS

Official Title

A Digital Intervention to Decrease Self-Stigma Among Pregnant and Postpartum Women With Substance Use Disorder

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women and new mothers up to 12 months postpartum
  • Adults aged 18 years or older
  • Fluent in English
  • Currently own or have daily access to a smartphone or tablet to use Enhearten
  • Self-report a history of substance use excluding alcohol, nicotine/tobacco, and prescribed drugs, or have this history documented by a healthcare provider
Not Eligible

You will not qualify if you...

  • Significant cognitive impairment that interferes with the ability to consent and complete study tasks, as self-reported or documented by a healthcare provider

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Washington University School of Medicine

St Louis, Missouri, United States, 63110

Actively Recruiting

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Research Team

A

Alex T Ramsey, Ph.D.

CONTACT

E

Elecia Worley, MSW

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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