Feasibility Study of Digital Monitoring Tools for Adults with Treatment-Resistant Depression Receiving Neuropsychiatric Treatments

What this Trial Is About

Researchers are exploring the use of digital tools to monitor mental health in adults with treatment-resistant depression. This study aims to find out if wearable devices like smartwatches or smart rings, combined with an electronic data platform, can be effectively used alongside regular clinical treatments such as repetitive transcranial magnetic stimulation rTMS, intravenous ketamine IVK, or electroconvulsive therapy ECT. The study also seeks to gather early clinical data to guide future, larger studies. Participants undergoing neuropsychiatric treatments for depression will have their clinical assessment scores for anxiety and depression recorded on a web-based platform after each treatment session. Additionally, they may wear a wearable device throughout their treatment period to passively collect health data like heart rate, temperature, sleep, and activity. This pilot study plans to recruit 200 adults over two years to evaluate how well these digital monitoring methods work in psychiatric care. During the approximately 2 to 8 weeks of treatment, participants will complete self-report or clinician assessments regularly, and their physiological data will be monitored continuously if they use the wearable device. Researchers will analyze feasibility, changes in symptoms, treatment response, remission, relapse, and personalized digital profiles. The study involves remote data collection and aims to integrate digital health monitoring into standard psychiatric treatment routines, with total participation spanning the treatment duration.

Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study