Actively Recruiting
A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trial
Led by Fred Hutchinson Cancer Center · Updated on 2026-02-09
776
Participants Needed
1
Research Sites
178 weeks
Total Duration
On this page
Sponsors
F
Fred Hutchinson Cancer Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial compares a new smoking cessation smartphone application (app) (IndigeQuit) to an existing smarphone app (National Cancer Institute \[NCI\] QuitGuide) for helping American Indians and Alaska Natives (AI/ANs) quit smoking. Compared to other racial/ethnic groups, AIANs have 6 times higher rates of developing smoking-related cancers, including lung cancer. Commercial cigarette smoking accounts for half of all deaths among AIANs nationwide. AIANs' often lack of access to smoking cessation interventions, which may be due to inequities in the healthcare system, lack of health insurance, living in rural areas, systemic racism, and historical trauma. There is also a lack of effective smoking cessation interventions for AIANs. Smartphone apps have the potential to deliver a low-cost smoking cessation intervention with wide reach to AIANs. Apps require no in-person delivery and no provider training, do not require integration into complex hospital systems, can be freely accessed on an app store, and are available at any time and any place. IndigeQuit is a behavioral intervention designed to help adults stop smoking by teaching skills for coping with smoking urges, staying motivated, and preventing relapse. The IndigeQuit app intervention may be more effective than the currently available NCI QuitGuide app at helping AIANs quit smoking.
CONDITIONS
Official Title
A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Self-identify as American Indian or Alaska Native, alone or with other races
- Age 18 years or older
- Smoked cigarettes daily for the past year
- Interested in quitting smoking within the next 30 days
- Willing to be randomly assigned to use either app
- Have daily access to own Android or iPhone smartphone
- Able to download a smartphone app
- Willing and able to read English
- Not currently or within past 30 days using other smoking cessation behavioral interventions or medications
- Have never participated in this research before
- No other household or family member participating
- Willing to complete follow-up assessments at 3, 6, and 12 months
- Provide email, phone number(s), and mailing address
- Live off US AI/AN tribal reservations or on five Northern Plains tribal reservations with study approval
You will not qualify if you...
- Currently or within past 30 days using other smoking cessation behavioral interventions
- Previous participation in this research
- Prior use of the NCI QuitGuide app
- Unwilling to complete follow-up surveys at 3, 6, and 12 months
- Not providing email, phone number(s), and mailing address
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109
Actively Recruiting
Research Team
B
Brie Sullivan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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