Actively Recruiting

Phase Not Applicable
Age: 40Years - 64Years
All Genders
NCT06582316

Digital Solution for Salutogenic Brain Health (DiSaB): A Pilot Protocol for Clinical Implementation

Led by National University of Singapore · Updated on 2025-05-22

160

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to develop and learn if a digitally delivered brain health intervention (DiSaB) can help improve cognitive, physical and psychosocial health in middle-aged adults with chronic conditions at-risk for cognitive decline. The clinical trial also aims to find out the push and pull factors of implementing the intervention in primary care settings. The main questions it aims to answer are: 1. Does the DiSaB intervention improve participants' cognitive functions, health measures, and psychosocial health? 2. Is an individualised or group-based health education session better at improving cognitive, physical and psychosocial health in participants who did not respond to the DiSaB intervention? 3. How useful and practical is the DiSaB intervention, according to 1. participants and 2. nurses carrying out the intervention? The investigators will compare a DiSaB intervention to a control condition (where participants do not undergo any intervention) to see if the DiSaB intervention works in improving participants' health. The investigators will also compare individualised versus group health education sessions to see which session is better at improving the health of participants who did not respond to the DiSaB intervention. Participants will 1. Complete cognitive assessments, questionnaires, and health tests before intervention, immediately after the intervention, and 6 months after the intervention 2. Either undergo no intervention, or undergo the DiSaB intervention over 2 months 3. Be randomly selected to attend focus group interviews Local champions will complete questionnaires and attend focus group interviews after administering and/or co-facilitating the intervention.

CONDITIONS

Official Title

Digital Solution for Salutogenic Brain Health (DiSaB): A Pilot Protocol for Clinical Implementation

Who Can Participate

Age: 40Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 40 - 55 years old
  • Have hypertension, hyperlipidaemia and/or type-2 diabetes
  • Ability to provide written informed consent
  • Possess sufficient English language skills in reading, writing and speaking
  • Multimorbidity conditions allowed except life-threatening conditions with less than one year life expectancy
  • Total Risk Score (TRS) for cognitive impairment of at least 3
Not Eligible

You will not qualify if you...

  • Physical, visual and/or hearing impairment
  • Language impairment such as severe dysarthria or aphasia
  • Not within the age range of 40 to 55 years old
  • Major or active psychiatric conditions
  • Diagnosis of dementia
  • Do not own a mobile device capable of downloading applications or lack internet access

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

National University Polyclinics

Singapore, Singapore

Actively Recruiting

Loading map...

Research Team

Y

YanHong Dong, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here