Actively Recruiting
Digital Solutions in Heart Therapy (DIGNITY)
Led by University Hospital, Basel, Switzerland · Updated on 2025-12-02
140
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to assess the safety and effectiveness of telemedicine guided strategy on guideline-directed medical therapy (GDMT) optimization in hospitalized patients with heart failure in comparison to usual care in Switzerland.
CONDITIONS
Official Title
Digital Solutions in Heart Therapy (DIGNITY)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years at the time of hospital admission
- Ability to use a smartphone and/or tablet for follow-up
- Documented left ventricular ejection fraction greater than 40% assessed within the preceding 12 months
- Not treated with optimal doses of oral heart failure therapies within 2 days before hospital discharge for acute heart failure in at least one medication category
- Hospitalized due to acute heart failure decompensation
- Systolic blood pressure greater than 100 mmHg and heart rate greater than 60 bpm within 24 hours prior to randomization
- Serum potassium less than 5 mmol/L within 24 hours prior to randomization
You will not qualify if you...
- Inability to use a smartphone or tablet
- Clear intolerance to high doses of beta-blockers, ACE inhibitors, or ARBs
- Estimated glomerular filtration rate less than 30 ml/min/1.73m2 or on dialysis
- Myocardial infarction, unstable angina, or cardiac surgery within 3 months prior to screening
- Percutaneous transluminal coronary intervention within 1 month prior to screening
- Cardiac resynchronization therapy device implanted within 3 months prior to screening
- Presence of significant obstructive lesion of the left ventricular outflow tract
- Amyloid cardiomyopathy
- Participation in other clinical drug trials
- Pregnant or nursing women
- Women of child-bearing potential unwilling to abstain from sexual intercourse or practice contraception
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
Research Team
Q
Qian Zhou, Prof. MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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