Actively Recruiting

Phase Not Applicable
Age: 12Years - 29Years
All Genders
ID06774417

Digital Strategies to Advance Help-Seeking in Youth at Clinical High Risk for Developing Psychosis

Led by Columbia University · Updated on 2026-03-23

25000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

U

University of California, San Francisco

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating digital methods to improve early help-seeking and speed up treatment for youth aged 12 to 29 who are at Clinical High Risk (CHR) for developing psychosis. The study aims to identify different help-seeking patterns in 25,000 young people who screen positive for psychosis risk using an online screening tool. This research is supported by a collaboration between Mental Health America, NIH-funded networks, and academic institutions to better understand and support early intervention in this vulnerable group. Participants will engage with digital strategies designed to encourage help-seeking behavior at key points: after online screening, during texting with peer navigators, and following clinical assessment. These digital nudges, based on the Health Action Process Approach (HAPA) model, include personalized messages targeting self-efficacy, perceived needs or risks, and expected outcomes. Participants are randomly assigned to different digital nudge groups throughout the study, aiming to find the most effective approaches to advance youth toward clinical care. During the study, participants complete the Prodromal-Questionnaire (PQ-B) online and may interact via text or video with peer navigators and clinicians. Researchers collect data on engagement, symptom severity, and help-seeking progress. The main outcomes measured include the proportion of youth who initiate texting or schedule assessments, complete clinical assessments, and advance to care within two weeks. The study will last from early 2026 to mid-2028 and includes ongoing monitoring of participants’ help-seeking steps and treatment initiation.

CONDITIONS

Brief Title

Digital Strategies to Advance Help-Seeking - Aim 3

Who Can Participate

Age: 12Years - 29Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 12 to 29 years
  • Living within a 50-mile radius of a US based AMP-SCZ site
  • Able to complete the English language PQ-B on Mental Health America's screening platform
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 baseline visit (online)

Surveillance

Duration - Up to 2 weeks

Participants complete the Prodromal-Questionnaire (PQ-B) and engage with digital help-seeking advancement strategies through online screening and text messaging to advance from intention to action towards care.

Ongoing online interactions and text exchanges as participants progress through study stages

Trial Site Locations

Total: 1 location

1

Columbia University Irving Medical Center

New York, New York, United States, 10032

Actively Recruiting

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Research Team

M

Michael Birnbaum, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

SCREENING

Number of Arms

4

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