Actively Recruiting
Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections
Led by Loma Linda University · Updated on 2025-11-19
1100
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a multicenter randomized controlled trial of 1100 patients to evaluate the superiority of combined intraoperative wound irrigation with intraoperative peritoneal lavage with dilute aqueous povidone-iodine compared to normal saline in male and female patients between the ages of 18 and 80 years old undergoing emergency laparotomies with Centers for Disease Control (CDC) class 2 and 3 wounds.
CONDITIONS
Official Title
Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 80 years of age
- Undergoing an exploratory laparotomy for Centers for Disease Control class II and III wounds
You will not qualify if you...
- Pregnancy
- Preoperative abdominal wall skin or soft tissue infection
- Allergy to iodine
- Patients unlikely to survive beyond 30 days
- Patients with mesh placement or placement of a foreign body except for drains
AI-Screening
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Trial Site Locations
Total: 1 location
1
Loma Linda University Health
Loma Linda, California, United States, 92354
Actively Recruiting
Research Team
M
Martin G Rosenthal, MD
CONTACT
M
Mohamed H El-Farra, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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