Study of Delayed Ischemic Neurological Deficit in Adults with Aneurysmal Subarachnoid Hemorrhage in Intensive Care

What this Trial Is About

Researchers are investigating delayed ischemic neurological deficits DIND in patients who have suffered aneurysmal subarachnoid hemorrhage aSAH. While survival rates for aSAH have improved, some patients develop chronic neurological problems like DIND, whose causes are varied and not fully understood. This study aims to describe how often DIND occurs, evaluate different diagnostic and treatment approaches, and assess the use of brain pressure monitoring during aSAH in a real-world clinical setting. This multicenter, prospective observational study will include patients diagnosed with aSAH confirmed by imaging, admitted to intensive care units, and receiving treatment as determined by their medical teams. The study does not assign treatments but collects data on how patients are diagnosed and managed, including monitoring methods and treatment intensity. Enrollment lasts 12 months from ethical approval, with a follow-up period of 12 months after the initial event. Participants will undergo clinical neurological assessments and monitoring to detect suspected DIND. Researchers will track mortality and neurological function using standardized scales at 6 and 12 months. The study also observes intracranial pressure changes in patients with pressure monitoring and the intensity of treatments applied. In total, approximately 1000 patients are expected to be enrolled to help understand outcomes and management strategies for DIND after aSAH.

DIND in Patients With aSAH : Real World Study