Actively Recruiting
Delayed Ischemic Neurological Deficit in Patients With Aneurysmal Subarachnoid Hemorrhage: Real World Study (DINDaSAH)
Led by Xuanwu Hospital, Beijing · Updated on 2026-01-02
10000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating delayed ischemic neurological deficits (DIND) in patients who have suffered aneurysmal subarachnoid hemorrhage (aSAH). While survival rates for aSAH have improved, some patients develop chronic neurological problems like DIND, whose causes are varied and not fully understood. This study aims to describe how often DIND occurs, evaluate different diagnostic and treatment approaches, and assess the use of brain pressure monitoring during aSAH in a real-world clinical setting. This multicenter, prospective observational study will include patients diagnosed with aSAH confirmed by imaging, admitted to intensive care units, and receiving treatment as determined by their medical teams. The study does not assign treatments but collects data on how patients are diagnosed and managed, including monitoring methods and treatment intensity. Enrollment lasts 12 months from ethical approval, with a follow-up period of 12 months after the initial event. Participants will undergo clinical neurological assessments and monitoring to detect suspected DIND. Researchers will track mortality and neurological function using standardized scales at 6 and 12 months. The study also observes intracranial pressure changes in patients with pressure monitoring and the intensity of treatments applied. In total, approximately 1000 patients are expected to be enrolled to help understand outcomes and management strategies for DIND after aSAH.
CONDITIONS
Brief Title
DIND in Patients With aSAH : Real World Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with aneurysmal subarachnoid hemorrhage confirmed by cerebral angiotomography or intracranial vessel angiography
- Admitted to an intensive care unit
- Signed informed consent form as required by local regulations
You will not qualify if you...
- Under 18 years of age
- Subarachnoid hemorrhage without a visible aneurysm, including traumatic cause
- Presence of brain tumors or arteriovenous malformations causing hemorrhage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 12 months
Participants who undergo routine care are observed to monitor the incidence of delayed ischemic neurological deficit and neurological-functional outcomes over time.
Visits occur during routine care up to 12 months after the acute event
Trial Site Locations
Total: 1 location
1
Department of neurosurgery, Xuanwu hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100053
Actively Recruiting
Research Team
L
Lidan Jiang
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here