Actively Recruiting

Phase Not Applicable
All Genders
Healthy Volunteers
NCT07532694

Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients

Led by Military Hospital 103 · Updated on 2026-04-16

80

Participants Needed

2

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis. Eighty participants will be allocated to two parallel groups: scaling and root planing (SRP) with adjunctive diode laser therapy or SRP alone. Clinical periodontal parameters, blood biomarkers, radiographic findings, and subgingival microbiome profiles will be assessed at baseline and during follow-up. The study aims to determine whether adjunctive diode laser therapy provides superior clinical and biological improvement compared with SRP alone.

CONDITIONS

Official Title

Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Kidney transplant recipients aged 18 years or older
  • Diagnosis of periodontitis according to the study case definition
  • Medically stable and able to undergo non-surgical periodontal treatment
  • Willing and able to provide written informed consent and attend follow-up visits
Not Eligible

You will not qualify if you...

  • Periodontal treatment or systemic antibiotic use within the predefined exclusion window in the protocol
  • Acute oral infection requiring urgent treatment
  • Pregnancy or lactation, if excluded by the approved protocol
  • Serious systemic condition or clinical instability judged by investigators to preclude study participation
  • Inability to comply with study procedures or follow-up schedule

AI-Screening

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Trial Site Locations

Total: 2 locations

1

103 Military Hospital

Hanoi, Hadong, Vietnam, 100000

Actively Recruiting

2

Vietnam Military Medical University

Hanoi, QUẬN HÀ ĐÔNG, Vietnam, 100000

Actively Recruiting

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Research Team

T

Thang V Dinh, Principal Investigator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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