Study of Changes in Eating and Drinking Behaviors and Gut Hormone Levels in Adults After Bariatric Surgery

What this Trial Is About

Researchers are investigating how bariatric surgery, including Sleeve Gastrectomy SG and Roux-en-Y gastric bypass RYGB, affects eating and drinking behaviors in people with obesity. The study focuses on understanding these behaviors beyond self-reported food intake by using a special device called the drinkometer. This research also explores differences between males and females and examines how changes in gut hormone levels relate to these behaviors and body weight loss over time. The study observes adults with obesity undergoing SG or RYGB surgery, as well as control groups including people with obesity not having surgery and individuals with normal weight. Using the drinkometer, the study measures detailed aspects of ingestive behavior before and up to one year after surgery. Additionally, it investigates hormone levels after eating and compares results between sexes. A subgroup of patients who had RYGB surgery five years ago is also studied to explore long-term associations between ingestive behavior, hormone levels, and weight loss. Participants will undergo assessments of their drinking behavior using the drinkometer device, and blood samples will be taken to measure gut hormone levels. Data collection occurs before surgery and at various times up to one year after, with a separate evaluation for those five years post-surgery. The study measures detailed behavioral patterns, hormone effects, and body weight changes to understand the impact of bariatric surgery. The total study duration varies depending on the participant group, and safety and adherence are monitored throughout the research period.

Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery