Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06538948

Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery

Led by University of Zurich · Updated on 2024-08-06

420

Participants Needed

2

Research Sites

185 weeks

Total Duration

On this page

Sponsors

U

University of Zurich

Lead Sponsor

F

Florida State University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity. Yet, the exact mechanisms governing its effect are somewhat elusive, with current research mainly focusing on post-operative food intake outcomes based on self-reported data, which might not fully capture the nuanced changes in eating behaviours. To address these gaps, our study plans to employ the newly developed "drinkometer", a device capable of analysing the intricate changes in drinking behaviour following BS. This tool promises to bring a more detailed perspective to the changes in ingestive behaviours, bypassing the inaccuracies of self-reporting methods. By expanding our research to encompass diverse patient demographics and examining potential links to physiological shifts like gut hormone level alterations, the study aims to provide a more rounded understanding of the long-term impacts of BS on eating behaviours.

CONDITIONS

Official Title

Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • BMI 35 kg/m2 or higher for patients planning Roux-en-Y gastric bypass or Sleeve Gastrectomy
  • BMI 30 kg/m2 or higher for external controls with obesity and no planned surgery within 12 months
  • BMI between 18.5 and 24.9 kg/m2 for controls without obesity
Not Eligible

You will not qualify if you...

  • History of previous bariatric operations or revisional surgery
  • Smoking
  • Established diagnosis of type 1 or type 2 diabetes mellitus
  • Polycystic ovary syndrome (PCOS)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Hospital Männedorf

Männedorf, Canton of Zurich, Switzerland, 8708

Actively Recruiting

2

University Hospital Zurich, Department of Surgery and Transplantation

Zurich, Switzerland, 8091

Actively Recruiting

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Research Team

M

Marco Bueter, MD, DPhil

CONTACT

M

Michele Serra, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

8

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