Actively Recruiting
Directional Versus Nondirectional DBS for ET
Led by Oregon Health and Science University · Updated on 2025-10-30
24
Participants Needed
1
Research Sites
443 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for the treatment of essential tremor (ET), effectively treats ET, and minimizes effects on speech, gait and balance compared to nondirectional DBS.
CONDITIONS
Official Title
Directional Versus Nondirectional DBS for ET
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have bilateral upper limb action tremor lasting at least 3 years
You will not qualify if you...
- Have decided not to receive DBS for medication-refractory essential tremor
- Have secondary tremor from medications or another neurological disease (e.g., multiple sclerosis, Parkinson's disease, dystonia)
- Have had prior deep brain stimulation
- Have had prior thalamotomy
- Have history or signs of dystonia, ataxia, or parkinsonism
- Have task-specific tremor
- Have orthostatic tremor
- Have cardiac pacemakers, defibrillators, or neurostimulators
- Require MRI, ECT, rTMS, or diathermy
- Have other types of neurological disease or injury
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Oregon Health & Science University
Portland, Oregon, United States, 97239
Actively Recruiting
Research Team
Z
Zoe Fanning
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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